Rett syndrome is a severe developmental disorder triggered by mutations in the MECP2 gene, which researchers have recently discovered compromises the structural integrity of developing brain blood vessels. This #genetic mutation causes the overexpression of a specific #microRNA that breaks down the tight seals of the blood-brain barrier, resulting in vascular leakiness that disrupts neural function.
#Neuroscience #CellBiology #Genetics #sflorg
sflorg.com/2026/03/ns03142601.…