Rett syndrome is a severe developmental disorder triggered by mutations in the MECP2 gene, which researchers have recently discovered compromises the structural integrity of developing brain blood vessels. This #genetic mutation causes the overexpression of a specific #microRNA that breaks down the tight seals of the blood-brain barrier, resulting in vascular leakiness that disrupts neural function.
#Neuroscience #CellBiology #Genetics #sflorg
sflorg.com/2026/03/ns03142601.…

Researchers created a comprehensive four-dimensional developmental atlas mapping the spatial and temporal activity of thousands of #genes in zebrafish embryos to understand their direct role in #cell maturation and #morphogenetic movement.
#Genetics #CellBiology #Biology #sflorg
sflorg.com/2026/03/gen03142601…

A novel stem cell therapy that integrates biodegradable #nanogel microfibers into three-dimensional cell clusters (#spheroids ) to enhance stem cell survival, oxygen diffusion, and functional regeneration of injured swallowing muscles.
#Bioengineering #MaterialScience #CellBiology #sflorg
sflorg.com/2026/03/beng0314260…

Connectome-seq is a high-throughput brain-mapping platform that employs unique RNA "barcodes" to tag individual neurons, facilitating the simultaneous mapping of thousands of neural connections at single-synapse resolution.
#Neuroscience #MolecularBiology #CellBiology #DevelopmentalBiology #sflorg
sflorg.com/2026/03/ns03142602.…